First approval of gene therapy (alters the person’s immune cells (T-cells) to fight cancer, also known as CAR-T therapy)1 2
Radioligands are an innovation driven by our increasing understanding of the molecular biology of cancer and the role of radiation in cancer care. This timeline explores the history and future of radioligand therapy (on the right) alongside other innovations in oncology (on the left).
First approval of gene therapy (alters the person’s immune cells (T-cells) to fight cancer, also known as CAR-T therapy)1 2
Approval of radioligand therapy for progressive midgut NETs in the EU3
Approval of bone-directed radiotherapy for mCRPC in the EU4
First approval of immune checkpoint inhibitor (for malignant melanoma)5
Further studies into radioligand therapy for bone metastases6
First monoclonal antibody immunotherapy treatment approved5
Approval of internal radiation therapy for pain in bone metastases in EU countries7 8
Early studies and use of radioligand therapy for NETs9-12
Early trials of radioligand therapy for bone metastases13
First scans of endocrine-related tumours using targeted radioisotopes14 15
First anti-cancer vaccine against hepatitis B virus (a risk factor for liver cancer)1 2
First hormone therapy approved that blocks the effect of oestrogen5
First use of chemotherapy after surgery (known as adjuvant chemotherapy)1
First PET scanner developed16
First use of chemotherapy1
Early trials of radioactive strontium to treat metastatic bone cancer17
Discovery of hormone therapy for prostate cancer5
First use of radioiodine to treat thyroid cancer (this was the first example of using a radionuclide for cancer treatment)18
First approach combining surgery and radiation5
First use of radiotherapy to cure cancer1
For more information about this project contact us: info@radioligandtherapy.com
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